Immune Library Screening
Immune Antibody Library
Y-Biologics can offer the construction of immune antibody libraries to provide more refined antibody candidates. Antibodies derived from an immune antibody library tend to have higher affinity against the designated targets compared with the antibodies discovered from conventional methods. Our dedicated team will construct bespoke immune antibody libraries for your specific project to screen targeting antibodies.
Schematic Diagram
-
01
Mouse immunization
-
02
Spleen lysis & mRNA extraction
-
03
RT-PCR
-
04
scFv phage library
Immune Body Screening Process
01Differentiated Services
-
Antibodies with higher
binding affinity -
Ideal for small size
target molecules -
Optimized for
neutralizing antibodies
02Screening Process
-
3MONTHS
- Mouse
immunization
- Mouse
-
1MONTH
- scFv phage
library
- scFv phage
-
1MONTH
- Biopanning
(3 rounds)
- Biopanning
-
1MONTH
- Monophage
analysis
- Monophage
-
1MONTH
- IgG
production
- IgG