Nanobody Library Screening
Human Nanobody Library (Ymax®-NANO)
Y-Biologics can offer the construction of single-domain antibody libraries(Ymax® NANO) to provide variable domain of the heavy chain antibody(VHH) candidates. Ymax®-NANO was developed utilizing the Ymax®-ABL human antibody discovery platform.
Conventional antibody
Single domain Antibody
- Ymax®-NANO Library
- CDR3 shuffling
- Camelization
- Backbone Selection
- Ymax®-ABL
Human VHH Screening Process
01Differentiated Services
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Framework
Human Germline
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CDR Source & Lengths
Naïve (human) & CDR3 (8-22a.a.)
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Library Size (CFU)
1 x 1010
02Screening Process
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4 WEEKS
Biopanning (3 rounds)
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4 WEEKS
Human VHH Screening
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1 WEEKS
Monophage analysis
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2 WEEKS
Final repoart
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1MONTH
IgG production