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YBIOLOGICS YBIOLOGICS

Y-SERVICE Antibody Services

Antibody Services

Y-SERVICE

Nanobody Library Screening

Human Nanobody Library (Ymax®-NANO)

Y-Biologics can offer the construction of single-domain antibody libraries(Ymax® NANO) to provide variable domain of the heavy chain antibody(VHH) candidates. Ymax®-NANO was developed utilizing the Ymax®-ABL human antibody discovery platform.

Conventional antibody

Single domain Antibody

  • Ymax®-NANO Library
  • CDR3 shuffling
  • Camelization
  • Backbone Selection
  • Ymax®-ABL

Human VHH Screening Process

01Differentiated Services
  • image

    Framework

    Human Germline

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    CDR Source & Lengths

    Naïve (human) & CDR3 (8-22a.a.)

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    Library Size (CFU)

    1 x 1010

02Screening Process
  • 4 WEEKS image

    Biopanning (3 rounds)

  • 4 WEEKS image

    Human VHH Screening

  • 1 WEEKS image

    Monophage analysis

  • 2 WEEKS image

    Final repoart

  • 1MONTH image

    IgG production